SCIENTIFIC INSTRUMENTATION

• 4x heater/shaker plate positions
  • heating up to 105°C
  • shaking up to 2,500 RPM
• 4x heater/cooler plate positions
  • heating up to 110°C
  • cooling down to 0°C
• 12x SBS plate positions (including any deep well or microtiter plates)
• 12x 50 mL conical tube positions
• 64x microcentrifuge tube or CE/HPLC vial positions
• Compatible with a wide variety of tubes (including opaque tubes for light sensitive samples)
• Robotic arm for movement of plates, lids, and racks around the deck and to/from integrations

8x Independent Single Channel Pipettes

• 1 μL to 1 mL volume (± 1%)
• 0.4 to 250 μL/sec aspirate/dispense rate
• 10 μL, 50 μL, 300 μL, 1,000 μL regular, widebore, and filtered disposable polypropylene tips
• Pre-aspiration/post-dispense mixing
• Fine-grained pipette tip aspiration and dispense position control
• Tip movement and speed control

1x Multichannel Pipette (96 Channels)

• Capable of any simultaneous rectangular pipetting up to dimensions 8×12
• 1 μL to 1 mL volume (± 2%)
• 0.4 to 250 μL/sec aspirate/dispense rate
• 10 μL, 50 μL, 300 μL, 1,000 μL regular, widebore, and filtered disposable polypropylene tips
• Pre-aspiration/post-dispense mixing
• Fine-grained pipette tip aspiration and dispense position control
• Tip movement and speed control

Workcell Integrated Pressure Filter

• 0 to 40 PSI independent pressure sources for each well
• Filter though SBS filter plates
• Collects in SBS deep well plates

Workcell Integrated Plate Reader

• Supports absorbance, fluorescence, and luminescence reads

Absorbance

• CCD detector
• 220 to 1,000 nm wavelength selection

Excitation

• Xenon flash lamp
• 1 to 100 flashes per well
• 320 to 740 nm excitation monochromator (8 nm bandpass)
• 680 nm laser (AlphaScreen)

Emission

• High voltage PMT detector
• 320 to 850 nm emission monochromator (8 nm bandpass)

Sample Injection

• 2x 500 µL injection syringes per batch
• 50 µL dead volumes, 0.5 µL precision
• 25 mL/min maximum injection speed
• 2 mL microcentrifuge tubes, 15 mL conical tubes, or 50 mL conical tube sources

Sample Chamber

• Room temperature (25°C ± 0.45°C (1 sigma)) to 45°C incubation
• Mix by shaking before read options
• 1x microtiter plate (6 to 96 well) per batch

• 3,000 RPM maximum speed (1,000 x g at Rmax)
• 250 x g maximum payload per bucket
• 10 g maximum imbalance
• 2 SBS plate footprint buckets
• 48.3 mm max plate height

Acoustic Liquid Handler

• Contact-free tipless liquid transfer
• 2.5 nL to 5 µL volume (± 10%)
• Dispense from 384-well Echo Qualified plates into any 96- or 384- shallow well SBS-format plates
• Fine-grained dispense position control allowing multiple distinct droplets per well
• Dispenses up to 200 droplets (500 nL) per second
• Rapid high-precision dispensing of small volumes of liquids
• Capable of handling high-viscosity aqueous solutions

Micropipettes

• Reverse pipetting available
• Aspiration dispense mixing (slurry transfers)
• Gravimetric transfers
  • Liquids can be transferred by weight (gravimetrically), from µg to kg, in both sterile and non-sterile environments
• Temperature controlled transfers
  • Temperature-sensitive source/destination samples can be marked to be chilled (4ºC) or heated (30 to 105ºC) during transfers (for more information, see Sample Transport section)
• Single-channel pipettes
  • 0.1 to 2.5 µL
  • 2 to 20 µL
  • 20 to 200 µL
  • 100 to 1,000 µL
  • 0.5 to 5 mL
• Compatible tip types
  • 10 μL reach tips, sterile
  • 20 μL barrier tips, sterile
  • 200 μL gel loading tips
  • 200 μL tips, non-sterile
  • 200 μL tips, sterile
  • 200 μL wide-bore tips, non-sterile
  • 1,000 μL wide-bore tips, non-sterile
  • 1,000 μL reach tips, sterile
  • 1,000 μL tips, non-sterile
  • 5,000 μL tips, non-sterile

Positive Displacement Pipettes

• Reverse pipetting available
• Aspiration dispense mixing (slurry transfers)
• Gravimetric transfers
• Temperature controlled transfers
• Temperature-sensitive source/destination samples can be marked to be chilled (4ºC) or heated (30 to 105ºC) during transfers (for more information, see Sample Transport section)
• Positive-Displacement Pipette MR-100
  • Min volume: 10 µL
  • Max volume: 100 µL
• Positive-Displacement Pipette MR-1000
  • Min volume: 100 µL
  • Max volume: 1 mL
• Compatible and supported tips
  • 100 µL positive displacement tips, sterile
  • 1,000 µL positive displacement tips, sterile

Serological Pipettes

• Reverse pipetting available
• Aspiration dispense mixing (slurry transfers)
• Gravimetric transfers
  • Liquids can be transferred by weight (gravimetrically), from µg to kg, in both sterile and non-sterile environments
• Temperature controlled transfers
  • Temperature-sensitive source/destination samples can be marked to be chilled (4ºC) or heated (30 to 105ºC) during transfers (for more information, see Sample Transport section)
• Variable dispense/aspirate speed (8 settings)
• 15 hours of continuous operation before recharging
• Compatible plastic serological pipette tips
  • 2 mL plastic barrier serological pipettes, sterile
  • 5 mL plastic barrier serological pipettes, sterile
  • 10 mL plastic barrier serological pipettes, sterile
  • 25 mL plastic barrier serological pipettes, sterile
  • 50 mL plastic barrier serological pipettes, sterile
• Compatible glass serological pipette tips
  • 1 mL glass barrier serological pipettes, sterile
  • 2 mL glass barrier serological pipettes, sterile
  • 5 mL glass barrier serological pipettes, sterile
  • 10 mL glass barrier serological pipettes, sterile
  • 25 mL glass barrier serological pipettes, sterile
  • 50 mL glass barrier serological pipettes, sterile

Syringes

• 1 to 60 mL max volume
• 2 different connection types: Luer-Lok and Luer-Slip
• Polyethylene barrel and polypropylene plunger syringes
• Luer-Slip
  • 1 mL disposable syringe
  • 50 mL disposable Luer-Slip syringe
• Luer-Lok
  • 3 mL sterile disposable syringe
  • 5 mL sterile disposable syringe
  • 10 mL Luer-Lok syringe
  • 20 mL disposable Luer-Lok syringe
  • 60 mL sterile disposable syringe
• Needles
  • 21 G x 1 in stainless steel single-use needle
  • 18 G x 4 in reusable stainless steel non-coring needle
  • 18 G x 6 in reusable stainless steel non-coring needle
  • 18 G x 12 in reusable stainless steel non-coring needle

Syringe Pump

• Dual syringes for continuous dispensing at constant flow rates for up to 72 hours
• Multiple syringes to choose from: 10 µL, 50 µL, 500 µL, 50 mL
  • Borosilicate glass, PTFE, PFA Fluid Path
  • Minimum flow rate of 0.003 µL/sec (10µL syringe)
  • Maximum flow rate of 6000 µL/sec (50mL syringe)
• Syringes attach to 12 or 18 gauge tubing and luer-lock
• Available in multipe transfer environments (BSC, Glove Box, Fume Hood, Lab Bench)

Graduated Cylinders

• Transfers of liquids and slurries
• Optional overhead mixing/heating during addition
• Cylinders
  • 10 mL glass
  • 25 mL polypropylene
  • 50 mL polypropylene
  • 100 mL polypropylene
  • 250 mL polypropylene
  • 500 mL polypropylene
  • 1 L polypropylene
  • 2 L polypropylene
  • 4 L polypropylene

Ampoule Handling

• 1 to 2 mL
• 5 to 15 mL
• 20 to 30 mL

Cell Aspirators

Handheld vacuum-aspirator with interchangeable adapter heads

• Pressure-sensitive button controls amount of vacuum applied to aspirate sample
• Adapter heads accept single-use, disposable tips and contain ejectors to exchange tips
• All parts may be autoclaved

Available adapter heads

• 8-channel head compatible with 200 µL pipette tips
• Single channel head compatible with disposable 2 mL aspirating pipettes