SCIENTIFIC INSTRUMENTATION
INSTRUMENTS MENU
SPECTROSCOPY
ExperimentNMR[]
Example applications include: 1D NMR spectra for various nuclei (1H, 13C, 19F, 31P) and Water suppression techniques (WATERGATE, Excitation sculpting, Presaturation)
ExperimentNMR2D[]
Example applications include: Correlation Spectroscopy (COSY), Double Quantum Filtered COSY (DQF-COSY), COSY-β, Total Correlation Spectroscopy (TOCSY), Heteronuclear Multiple Bond Correlation (HMBC), Heteronuclear Single Quantum Coherence (HSQC), HSQC-TOCSY, Heteronuclear Multiple Quantum Coherence (HMQC), HMQC-TOCSY, Nuclear Overhauser Effect Spectroscopy (NOESY), Rotational Frame Nuclear Overhauser Effect Spectroscopy (ROESY)
500 MHz NMR
- 500 MHz for ¹H
- 126 MHz for ¹³C
- 202 MHz for ³¹P
- 470 MHz for ¹⁹F
Probe
- SmartProbe ¹H/¹⁹F/¹³C/³¹P 5 mm probe (-150°C to 150°C)
- Inverse Triple Resonance (TXI) ¹H/¹³C/¹⁹N 5 mm probe (-150°C to 150°C)
Autosampler
- 6 to 51°C incubation temperature
- 480 NMR tubes per batch
- Standard NMR tubes hold 600 µL to 1.5 mL
- Micro NMR tubes hold 40 µL
2D Experiment Types
- Correlation spectroscopy (COSY)
- Double-quantum filtered COSY
- COSY featuring a 45 degree pulse
- Total correlation spectroscopy (TOCSY)
- Heteronuclear single quantum correlation spectroscopy (HSQC, 1H-13C or 1H-15N)
- Heteronuclear multiple quantum correlation spectroscopy (HMQC)
- Heteronuclear multiple-bond correlation spectroscopy (HMBC, 1H-13C or 1H-15N)
- HSQC-TOCSY (1H-13C)
- HMQC-TOCSY (1H-13C)
- Nuclear Overhauser effect spectroscopy (NOESY)
- Rotating-frame Overhauser effect spectroscopy (ROESY)

ExperimentAbsorbanceSpectroscopy[]
Example applications include: Substance Quantification, Substance Identification, Analytical Chemistry, Analytical Biochemistry, Organic Compound Analysis
ExperimentFluorescenceSpectroscopy[]
Example applications include: Molecular Fluorescence, Fluorescence Properties, Substance Identification, Substance Quantification, Organic Compound Analysis, Analytical Chemistry, Analytical Biochemistry
ExperimentLuminescenceSpectroscopy[]
Example applications include: Protein Structure, Molecular Luminescence, Luminescence Properties, Impurity Detection, Substance Identification, Substance Quantification, Organic Compound Analysis, Analytical Chemistry, Analytical Biochemistry
Multimode Plate Reader w/ Monochromators
Excitation
- Xenon flash lamp
- 1 to 100 flashes per well
- 340 to 740 nm excitation monochromator
Emission
- High voltage PMT detector
- 340 to 740 nm emission monochromator
- Top or bottom of plate read mode
Sample Chamber
- Room temperature (25°C ± 0.45°C (1 sigma)) to 45°C incubation
- Mix by shaking before read options
- 1x microtiter plate (6 to 1,536 well) per batch

ExperimentFluorescencePolarization[]
Example applications include: Receptor-Ligand Binding, Enzymatic Degradation, DNA Hybridization
ExperimentIRSpectroscopy[]
Example applications include: Receptor-Ligand Binding, Enzymatic Degradation, DNA Hybridization
ExperimentDynamicLightScattering[]
Example applications include: Scattered Light Intensity, Brownian Motion, Moving Particles, Particle Size, Polydispersity, Isothermal Stability, Colloidal Stability, Attractive Interaction, Repulsive Interaction
Multimode Spectrophotometer
Multimode Spectrophotometer
- Measurement in sealed quartz capillaries requires only 9 μL of sample
- Measure up to 48 samples in one experiment
- Z-average diameter, polydispersity, isothermal stability, B22, kD, and G22
Dynamic Light Scattering
- 660 nm laser
- Avalanche photodiode module scattered light detector
- 0.3 to 1,000 nm hydrodynamic radius range
- < 0.1 polydispersity
- 0.05 mg/mL minimum sample concentration
- 192 Da to 25 MDa molecular weight range
Thermodynamics

DLS Plate Reader
- 830 nm laser
- 0.5 to 1000 nm hydrodynamic radius range
- 1000 to 1 MDa molecular weight range
- 0.125 mg/mL minimum sample concentration
- 4 to 85ºC temperature control
- Support standard 96, 384 or 1,536 microwell plates
- 4 µL minimum sample volume

ExperimentAbsorbanceKinetics[]
ExperimentFluorescenceKinetics[]
ExperimentFluorescencePolarizationKinetics[]
Example applications include: Protein-Protein Interaction, Live Cellular Monitoring, Reaction Kinetics Analysis, Enzyme Kinetic Measurements, Binding and Dissociation Analysis
ExperimentLuminescenceKinetics[]
Example applications include: Luciferase Reporter Gene Assays, ATP-based Cell Viability Assays, Cytotoxicity Assays, Protein-Protein Interaction, Live Cellular Monitoring, Reaction Kinetics Analysis
All Readers
Sample Chamber
- Room temperature (25°C ± 0.45°C (1 sigma)) to 45°C incubation
- Mix by shaking before read options
- 1x microtiter plate (6 to 1,536 well) per batch
Sample Injection
- 2x 500 µL injection syringes per batch
- 50 µL dead volumes, 0.5 µL precision
- 25 mL/min maximum injection speed
- 2 mL microcentrifuge tubes, 15 mL conical tubes, or 50 mL conical tube sources



Multimode Plate Reader w/ Monochromators
- 96-well plate compatible
Excitation
- Xenon flash lamp
- 1 to 100 flashes per well
- 340 to 740 nm excitation monochromator
- 680 nm laser (AlphaScreen)
Emission
- High voltage PMT detector
- 340 to 740 nm emission monochromator
- Top or bottom of plate read mode

Multimode Plate Reader w/ Filters
- 96-well plate compatible
Excitation
- Xenon flash lamp
- 1 to 100 flashes per well
- 355 nm, 410 nm, 485 nm, 544 nm, 584 nm, 650 nm, or 700 nm fixed wavelength excitation filters (5 nm bandpass)
Emission
- High voltage PMT detector
- 420 nm, 460 nm, 520 nm, 590 nm, 620 nm, or 750 nm fixed wavelength emission filters (5 nm bandpass)
- Top or bottom of plate read mode

Fluorescence Polarization Plate Reader
Sample Injection
- 2x 500 μL injection syringes per batch
- 50 μL dead volumes, 0.5 μL precision
- 25 mL/min maximum injection speed
- 2 mL microcentrifuge tubes, 15 mL conical tubes, or 50 mL conical tube sources
Sample Chamber
- Room temperature (25°C ± 0.45°C (1 sigma)) to 45°C incubation
- Mix by shaking before read options
- 1x microtiter plate (6 to 1,536-well) per batch
Optics
- Xenon flash lamp
- 1 to 100 flashes per well
- High voltage PMT detector
- Top or bottom read mode
Polarization Filters
- Excitation (vertical), Emission (vertical), Emission (horizontal)
- 485 nm, 520 nm, 520 nm
- 540 nm, 590 nm, 590 nm
- 625 nm, 675 nm, 675 nm

ExperimentNephelometry[]
Nephelometer
Sample Injection
- 2x 500 µL injection syringes
- 440 µL/s maximum injection speed
Sample Chamber
- Room temperature to 65°C incubation
- Actively regulates O2 and CO2 to 0.1-20%
- Mix by shaking before read options
Optics
- 635 ± 10nm 1mW self-monitoring laser diode
- 1.5 to 3.5 mm selectable beam width
- Side window photodiode detector
- Detects up to 80° full cone angle

ExperimentCircularDichroism[]
Circular Dichroism Plate Reader
- Dual gratings monochromator
- 185 to 880 nm wavelength range (2 nm resolution)
- 96 well plate format
- 2 minute read time for plate (single wavelength)
- 1 hour read time for plate (full spectrum)
- 0.5 L nitrogen gas/min purge
- 45 µL sample volume

ExperimentThermalImaging[]
Thermal Camera
- Object Temperature Range: -20 to 400°C (-4 to 752°F)
- Accuracy: ±3°C (at 0 – 100°C) and ±3% (at 100 – 400°C)
- Resolution: 5 Megapixels
- Focus: fixed, 0.1m minimum distance
- Image Frequency: 8.7Hz
- Spectral Range: 8 to 14µm

ExperimentNIRImaging[]
ExperimentSWIRImaging[]
ExperimentIRSpectralImaging[]
VIS-SWIR InGaAs Camera
- High sensitivity digital VIS-SWIR camera
- Sensor Type: InGaAs PIN-Photodiode
- Active Pixel: 640 x 512
- Pixel Pitch: 15µm x 15µm
- Active Area: 9.6mm x 7.68mm
- Spectral Response: 0.6 to 1.7µm
- Readout Noise (rms): < 50 electrons
- Frame Rate: up to 120Hz
- Exposure Time: 10µs to 26.8s
- Onboard Automated Gain Control (AGC)
- Ultra compact, Low power

ExperimentNIRFluorsecenceSpectroscopy[]
Fluorometer
- Signal-to-noise ratio 30,000:1 or better
- Data acquisition rate: 1,000,000 to 1 point/1000 sec
- Inputs: 4 photon counting (TTL); 4 analog (+/- 10 volts) ; 1 analog reference channel (+/- 10 volts); 2 TTL
- Outputs: 2 analog (+/- 10 volts) 2 TTL
- Emission Range: 185 to 900 nm
- Light Source: High efficiency “ECO” friendly continuous
- 75 W Xenon arc lamp
- Monochromator: Coma-aberration corrected, asymmetrical, excitation or emission optimized, Czerny- Turner design
- Focal Length: 350 mm
- Slits: Computer controlled, continuously adjustable
- Emission Grating: 1200 line/mm 400 nm blaze
- Wavelength Accuracy: +/- 0.3 nm
- Minimum Step Size: 0.022 nm
- Detection: Multimode – Photon Counting, 3 analog (fast, medium, slow response), direct and Single-Shot Transient Digitizer (SSTD) mode
