Property Measurement


ExperimentImageSample[]

Example applications include: Sample appearance, Identifying precipitate formation, Visualizing color change, Verifying sample integrity

Plate Imager Robotics

Overhead Imaging (Multiwell Plates)

  • 5 megapixel close-up images on a per-well basis
  • Fields of view: 22 mm and 35 mm
  • Lighting: Top or bottom LED illumination, or ambient
  • Imaging interval: 9 sec
  • Camera travel speed: Up to 5 m/min

Large Sample Camera

Side-on Imaging (Bottles and Other Vessels)

  • Canon Rebel Ti EOS 750D
  • 24.2 megapixel images
  • 18, 24, and 55 mm focal lengths to accommodate containers ranging from 8 mm glass vials up to 20 L carboys
  • Lighting: Top, bottom, or side (trans-) LED illumination, or ambient

Top Imaging (Bottles and Other Vessels)

  • 14 megapixel images
  • 12 mm fixed focal length lens
  • Lighting: Top, bottom (trans-), or side LED illumination, or ambient

ExperimentMeasureVolume[]

Example applications include: Quantification of liquid samples, Gravimetric volume measurement, Ultrasonic volume measurement, Non-contact volume detection, Liquid-level detection, Measure sample meniscus height

Ultrasonic Detectors

Ultrasonic Sensor Methods Available

  • Compatible with any parameterized container
    • Microcentrifuge tubes or SBS style plate wells (including 24-, 48-, 96-, and 384-well plates; ± 125 µL)
    • 15 mL conical tubes (± 55 µL)
    • 50 mL conical tubes (± 230 µL)
    • 250 mL bottles (± 5 mL)
    • 500 mL bottles (± 5 mL)
    • 1 L bottles (± 10 mL)
    • 2 L bottles (± 10 mL)
    • 4 L jugs (± 20 mL)
    • 5 L bottles (± 20 mL)
    • 10 L carboys (± 100 mL)
    • 20 L carboys (± 100 mL)

Balances

Gravimetric Volume Measurement Available

  • Requires samples with known densities in single sample containers
  • 1 µg to 60 kg measurement range to determine volume

ExperimentMeasureCount[]

Example applications include: Tablet weight, Tablet mass, Average tablet mass, Sample count

Balances

  • 100 µg to 220 g (± 100 µg)

ExperimentMeasureWeight[]

Example applications includeDetermine sample mass, Microanalytical balance, Analytical balance, Macro balance, Bulk scale, Accurate mass, Reproducible mass

Microbalance

  • 1 µg to 6 g (± 1 µg)

Analytical Balance

  • 100 µg to 220 g (± 100 µg)

Macrobalance

  • 120 g to 6.2 kg (± 10 mg)
  • 30 cm x 40 cm measurement platform

Bulk Balance

  • 5 to 50 kg (± 10 g)
  • 75 kg max mass tolerance
  • 42 cm x 55 cm measurement platform

ExperimentMeasureConductivity[]

Example applications include: Conductivity Measurement, Buffer Conductivity, Solution Conductivity, Solution Resistivity, Buffer Resistivity, Salinity Measurement, Total Dissolved Solids Measurement, TDS Measurement

Conductivity Meter

  • 0.001 µS/cm to 2,000 mS/cm conductivity measuring range
  • 0.001 µS conductivity resolution
  • ± 0.5% conductivity accuracy
  • Built-in temperature sensor for temperature correction
  • Linear, non-linear and pure water temperature compensation algorithms
  • 150 µL minimum sample volume

ExperimentMeasureDensity[]

Example applications include: Physical Property Measurement, Density Measurement, Solution Density, Buffer Density, Density Meter

Density Meter

U-tube Oscillation Measurement Method

  • 0 to 3 g/cm³ density measurement range
  • 7×10⁻⁶ g/cm³ density measurement accuracy
  • Reproducibility of 5×10⁻⁷ g/cm³
  • 5 to 100°C temperature control range
  • 0.01°C temperature accuracy
  • Automatic viscosity and temperature correction
  • 1.5 mL minimum sampling volume
  • No restrictions on containers

Fixed Volume Weight Measurement Method

  • 50 μL to 1.5 mL sampling volume per measurement
  • 1 μg to 5 g (± 0.8 μg) weight range
  • No restrictions on sample volume or containers
Anton Paar DM5000

ExperimentMeasurepH[]

Immersion pH Meters

  • pH range 0 to 14 pH (± 0.02)
  • 50 µL minimum sample size (consumes no volume)
  • Measures and records pH over time
  • Temperature correction

ExperimentMeasureMeltingTemperature[]

Melting Point Apparatus

  • 25°C (room temperature) to 400°C
  • Heating rate from 0.1 to 20°C/minute
  • Color video of samples throughout heating cycle (up to 300 minutes)
  • Up to 6 capillary samples per heating cycle

ExperimentMeasureRheology[]

Rheometer/Dynamic Mechanical Analyzer Instrument

  • Minimum torque (rotation) 1 nNm
  • Minimum torque (oscillation) 0.5 nNm
  • Maximum torque 230 mNm
  • Minimum angular deflection (set value) 0.05 µrad
  • Maximum angular deflection (set value) ∞
MCR 702e MultiDrive

ExperimentMeasureZetaPotential[]

ExperimentMeasureParticleSize[]

Zeta Potential Analyzer and particle analyzer

Applications

  • Proteins, IgG, peptides, RNA/DNA
  • Liposomes, exosomes, and other biocolloids
  • Polysaccharides
  • Nanoparticles
  • Polymer latexes
  • Pharmaceutical preparations
  • Micelles
  • Oil/Water and Water/Oil emulsions
  • Paints and pigments
  • Colloids
  • Polymers
  • Pigments, inks and toners
  • Cosmetic Formulation
  • Ceramics and refractories
  • Emulsions (foodstuffs, cosmetics)
  • Wastewater treatment monitoring
  • Carbon blacks
Brookhaven – NanoBrook Omni

ExperimentMeasureViscosity[]

Example applications include: Viscosity Measurement, Shear Stress Measurement, Shear Rate Measurement, Deformation Resistance Measurement, Shear Stress Response

Robotic Viscometer

  • Viscosity measurable from 0.3 to 1,000 mPaS (± 2% accuracy)
  • Shear rate range 40 to 125,000 1/s
  • 4 to 70ºC measurement temperature range
  • Minimum 26 μL sample volume
  • Sample constraints:
    • Up to 40 HPLC/CE vials
    • 1x 96-well PCR plate

ExperimentDifferentialScanningCalorimetry[]

Differential scanning calorimetry

  • Baseline Flatness (-50 to 300°C): ≤5 μW
  • Baseline Repeatability (-50 to 300°C): <10μW
  • Temperature Range: -180°C to 725°C
  • Temperature Accuracy: ±0.025°C
  • Temperature Precision: ±0.005°C
  • Enthalpy Precision: ±0.04%
TA Instruments – DSC 2500

ExperimentMeasureRefractiveIndex[]

Refractometer

  • 1.26 to 1.72 Refractive Index (RI) scale measurement range
  • 1×10-6 RI measurement resolution
  • ± 2×10-5 RI measurement accuracy
  • 0 to 100% Brix scale measurement range
  • 0.001% Brix scale resolution
  • ± 0.015% Brix scale accuracy
  • 4 to 85°C temperature measurement range
  • ± 0.03°C temperature measurement accuracy
  • Sapphire optical measurement plate

Sample Compatibility

  • All sample containers compatible
  • ~0.2 mL sample measurement volume

ExperimentDynamicMechanicalAnalysis[]

Dynamic Mechanical Analyzer

  • Force Range: 0.0001 to 18 N
  • Force Resolution: 0.00001 N
  • Frequency Range: 001 to 200 Hz
  • Dynamic Deformation Range: ±0 005 to 10,000 µm
  • Strain Resolution: 0.1 nm
  • Modulus Range: 103 to 3×1012 Pa
  • Modulus Precision: ± 1%
  • Temperature: -160 to 600°C

Dynamic Light Scattering Plate Reader

  • Supported Well Plate Formats: 96, 384 or 1536

Dynamic Light Scattering

  • Size Range (Radius, Rh): 0.5 to 1000 nm
  • Minimum Concentration @ 14 kDa: 0.125 mg/mL

Static Light Scattering

  •  Molar Mass Range: 1000 Da to 1 MDa
  • Minimum Concentration @ 67 kDa: 1 mg/mL

Optics

  • Laser Wavelength: 830 nm
  • Laser Power Control: Programmable 10% – 100%
  •  Attenuation Range: 1 to 105

Temperature Control: 4 to 85 °C 

Fluidics

  •  Minimum Sample Volume: 4 µL

Data Acquisition Time: 1 to 3600 seconds per well per read

Read Time per Well: 5 – 20 seconds

Electronics

  • Correlator: 512 channels 
  • Onboard Camera: 3 megapixels 
  • Digital Communication: Ethernet (TCP/IP)
Wyatt – DynaPro Plate Reader III

ExperimentThermalGravimetricAnalysis[]

Thermal Analyzer

  • High Temp Premium TGA/DSC with Sample Robot
  • Capacity: 900 uL
  • Temperature Range: Ambient to 1,600ºC
  • Heating Rate: 100 K/min
  • Accuracy: ± 0.5 K

Thermogravimetric Analysis Instrument

  • Temperature Range – Ambient to 1200 °C
  • Temperature Accuracy – ±1 °C
  • Temperature Precision – ±0.1 °C
  • Heating Rate (Linear) – 0.1 to 500 °C/min
  • Heating Rate (Ballistic) – >1600 °C/min
  • Furnace Cooling (Forced air/N2) – 1200 °C to 35 °C
    in <10 min
  • Sample Weight Capacity –  1000 mg
  • Dynamic Weighing Range –  1000 mg
  • Weighing Precision – ±0.01 %
  • Resolution – <0.1 µg
  • Weight Baseline Drift (Ambient to 1000 ˚C) – <10 µg
  • Vacuum – 50 µtorr
TA Instruments – TGA 5500

ExperimentCyclicVoltammetry[]

Example applications include: Redox (reduction and oxidation) Process, Electrochemistry, Electrochemical Analysis, Chemical Reactions, Catalysis

Electrochemical Reactor

  • Cyclic voltammetry electrodes
    • Glassy carbon 3 mm disc
    • Platinum plated
    • Ag, Ag/AgCl, Ag/Ag+ reference electrode options
  • Pro-Seal vial caps available for reactions requiring controlled atmosphere
  • Supports both aqueous and non-aqueous solutions
  • 5 mL, 10 mL, and 20 mL vial sizes
  • Large potential window: ± 2.5 V
  • CV voltage reading accurate to ± 1 mV
  • CV current reading accurate to ± 1 µA
  • Can stir reaction vessels from 50 to 1,500 RPM

ExperimentMeasureDissolvedOxygen[]

Example applications includeWater Quality, Degas Efficiency, Biological Reactions

Dissolved Oxygen Meter

  • 0 to 50.00 mg/L dissolved oxygen measuring range
  • 0.01 mg/L dissolved oxygen resolution
  • Built-in temperature and barometric pressure sensor for correction
  • 25 mL minimum sample volume

ExperimentMeasureOsmolity[]

Example applications includeVapor Pressure Osmometry, Formulation Development, Quality Control, Polymer Analysis, Serum Osmolality, Urine Osmolality

Osmometer

Vapor Pressure Osmometry Method

  • 20 to 3,200 mmol/kg osmolality measurement range
  • 1 mmol/kg osmolality resolution
  • ± 1% accuracy within 100 to 1,000 mmol/kg calibrated range
  • ± 5% accuracy outside of calibrated range
  • Reproducibility of 2 mmol/kg standard deviation
  • 10 μL sample volume
  • Aqueous samples